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R package

You can run MIMP locally by installing the R package from github. For documentation and a pdf manual on how to use it, please see the github page.

Datasets

Below are freely available datasets used by MIMP:

• TCGA rewiring events Pre-computed rewiring events for TCGA pan-cancer SNVs as a tab-delimited file
• Phosphorylation data Tab delimited file of phosphorylation data combined from public databases.
• Mutation data Tab delimited file of all TCGA non-synonymous SNVs used.


• Kinase-substrate data before and after refinement Substrates for each kinase before iterative refinement in FASTA format
• Kinase family substrate data before and after refinement Substrates for each kinase family before iterative refinement in FASTA format
• Negative phosphorylation data Flanking regions of S, T and Y residues not known to be phosphorylated in FASTA format


• Kinase sequence logos Sequence logos for all kinases used by MIMP. Sequence logos are generated using WebLogo.
• Kinase family sequence logos Sequence logos of kinase families.
• Predicted kinase sequence logos Sequence logos of predicted kinase specificity models.